Self-employed individuals can deduct premiums for their health coverage as an above-the-line deduction under certain conditions; no itemizing is required. While the IRS has never specifically said the COBRA premiums count as self-employed health insurance, it appears to be deductible as an above-the-line deduction for a self-employed individual paying these premiums.
Generally, itemized deductions for job and investment expenses subject to a 2% of adjusted gross income floor.